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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96fd48999ade546c09bde1e382a1beef7b5b4ff22dfdf53153c68b54121b64f0' 
  AND token = 'rJe+KZm+Pc+PzpKHpFX9Bi29cL3W8KqYk3rxeNU1Dyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}