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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '190c3e2d92d6835bc5322dbb9981a8d7f878c1a1eff5d4d9e683113c45213062' 
  AND token = 'mr1wtsWFzV21tcQbVSWBNaMLjWiwoy4/JOWI6zjkgh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}