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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bc6a706379698697ac785c9c4ab0c33e113204287ecf79ff22e800a1051eeaa' 
  AND token = 'fAjq7ZYxCrlTP1mBgYU09B1jI7cMaAZ3lzQMM2uTCI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}