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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a842311038f494404a7dd3f03758c62b981d6d9baffcb6e2300624c45e550fa' 
  AND token = 'nQtkF4PL0o+/lBRodt0yTyhCTZPfQIJf8QdsPjywlTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}