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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478ec86c4f9bf158e4071aaf8632c831268339ba3ac392f5e0c3305d9d057143' 
  AND token = 'h0YEM8zpp5O6WT5nmKNYQa+d8VMlSzq5Mt7X+Ni1pr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}