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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e07dccf68d2a7b3f482e7d7ed0cf15cc18506fa26b7351ec52c894c0e4e4cc' 
  AND token = '0qq58qfZVCBSOz/u2tWulM/GExnHzBv6/0jMG2X8jnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}