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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7716a49b7b9fcc3aa3b321cac94f26c37b76ee37c9199ce3c6386c175bd425a5' 
  AND token = '5tPUO2e+bqTwtvqCIIAaJZiUosW7MTLxLPC3XWOvWEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}