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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc8e76735ab4cc879a92c074af04258d4c4dd5cd3ee5d931cc64bf067b4c441f' 
  AND token = 'g1kb/FqXUY+t/8UFzMAx+fNnwz2Cp0+BYwTOeaITwq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}