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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99537d9abe99c4868708fb79faa114b888dcfecbb0d668d5b2404601e5ec757a' 
  AND token = 'YCmwdpyINl+8YauugR20LveS3ZDSYbtzNxSrBiQ4FlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}