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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffd2cfa4069562b54a02f0b99ce03f3720551b86058d503ddeda1d1b1f4a777a' 
  AND token = 'VidkJsCtd6Qln5SCHLhf5fsGM8dIIK6Z24Dp7gvSaUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}