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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc5a42f9d6b7bfea9e9bbc6585fa23f8a92d8b9611a6f9590a014daab422f838' 
  AND token = 'SG51IW4lT5KiuUIiktbOBz9xvDBNUBcWMTcLWtPfvEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}