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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b40bb9c702398a7c845f43d59a2cfc0d607c89ad6c1f7515a4e720060dac78' 
  AND token = 'NuRMi50d0gJrlPVwZMJkPk5fZ1gId8v0fgJzOKZ0Sek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}