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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbd133adf651650ee0b1d3c97ee9c0f7a8dd49959c43b5744e7135a24f9519f5' 
  AND token = 'sQD/+duNkX4COtAQLgZVZVB8XXkNVo+JJzaY82n3kLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}