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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0148e3356b20eeeb005c9703a5b6a6dd4b5c4a04c015971e700498c75c85bf98' 
  AND token = 'PVMLQ1p4rpjf5DalJaNb4HMBQlib5ubhYZyLu0shk/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}