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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca97a25b12ad56a1e421609d25d7886f1483d2a731b65d715a9e47d164f18218' 
  AND token = 'C9zNoLPHXgGTlv93DM1fxgZGS5xAM8bOsmyhajh0aB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}