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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e40b9039d6fd7d424acc9489cbe4d3003dc1a54ab89ec3781785165c2ea9210' 
  AND token = 'd8POBqubArqa+c7YpwjOB4r1i59yYuiQcwBfsgh3sbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}