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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8137fcd85c6953503ec8654d876300f4f812fb0b99c4782f47ecff1f05528c' 
  AND token = 'yROq3U42rErnNuEp1+gts+wdpxlkDYCKXD8hnYC8v7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}