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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '935bc003284b4703778a9120dd499b32380ff2995e3b871546891cb1ab61117f' 
  AND token = 'Nudv9E6bU6VE2oFN0z8ch37n3Ma7So8MdHmCo4ij1Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}