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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c1c918847791d33fa7e5048439396e5e2d2d151dc7ad1818865ab841ae8c79' 
  AND token = '9RBIFe6jPl2vzZcH4mmAJD8mqT5BkUW6ytu9M0I2VU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}