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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765514caaf78e83497c930aecefb760e31006ff6132bab401fa9cdf4e8353142' 
  AND token = 'aXXZfP1udIDHz5FojXbSO9YlNo5XK/BM/G1UjC17/xY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}