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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d222680b5c19ff2626cdd2cf145cba374f66637955c1fbd82326fe45458d5b9' 
  AND token = 'PUfGnpDn8Z0F0pg+5THUyWsJKS/vN00Ny8Q1iCK2/OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}