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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa4284aeffbcbe2b6dc833eb304e9929c45c6b0618fa1a45a9f66bcd5bd1a81' 
  AND token = 'cX+o43T9n5GOmjTVKIw8tRlkubuGawzT6WXpJMqMQTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}