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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4d976718d4028dfd8fcfa1408ecfd419eec5c2f80c509c6bfd44ff13a33743' 
  AND token = 'UZXvsi2djb1BXH1SZUsoPxKJOXW9OkIAlGznw71Hpno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}