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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727398e0550445970f531c2ba8e1b7aea6cf62bd632c102b58ccef37bcdac30d' 
  AND token = 'azBOrWXzaaXGxmWxG8QyMi75WO73bPdkEFM8xYumm4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}