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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55bdcd67a4eab0f83d0e79d3528c14718a8330d11a62f95731edfa36a4f322b6' 
  AND token = 'EPPGrXIu6pZN4tAhzOposO9FCCjiwsxuT2Tek93YXF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}