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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a9890b23b51f97a36036853aa790b69fddc719fd3a14d4c91f1c2502e32e92' 
  AND token = 'OrR0D+LiU82bbbqyxBAjaoaPkh56KKYn5gpLn7zdRC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}