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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ca83d0dba40aeb530b19dd290d6a1b7faf7137014f0d09a1f160615008ce16' 
  AND token = 'MjnZKYamZ6Qntl1r2awVLW1I0g0jeHJcL6Fx0GDW6tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}