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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df95960ea0e6a8217f62e74cf9868328a9a54e60d70338d5eace3a3309113c52' 
  AND token = '/5+2PCRACkAI5HmRxrQrHNTTlmANkfQlPdBRgyG6tUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}