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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd91ff21abdc4afb9055eff5b88b024c09f03d63fbfe0e52d51e78b5ea833842f' 
  AND token = 'l/GZiov2ngqv/QgOjETH8+Z9RO8sWCFKNFdo11KQvt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}