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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b112316b00787209c20b3a5fb6f3712874ca309d4cf3d44dce54bea12382d38c' 
  AND token = 'PZVOh6jsMCiM3StQnvq3/81iit0bYQXLsaGQtRWU+O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}