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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c64db20eab51bac691f7942316c6784a96f5d520ab0cae202f8c611c45b4aba' 
  AND token = 'To/G7IiRNeiT2EgCHHGZE+6LT9R0zIEE4B5X8GgfYgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}