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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5554a4045c8b45c32c083d1df5530e5fe19eb85e4233a24816f93c6536393e' 
  AND token = '/lHGIbYTiVd8tYJo5kTucLp93tg1Y9glB7LXVe2gXKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}