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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd907a576a24fb13d5a5ddc05c13c7b0ceacd90ee30104dc4247c98e6177461' 
  AND token = '2/CMX8Dl62R8I1+yO0vI0d50ziKF5OvwVOWud6HziP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}