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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0be43b52bfd1c836690b70928177f605cd2cd11adc924ea37ff10ccf99a6c1' 
  AND token = 'ZU1uMMDjI5W0flodOKvleEAtrPPXJqQ2M8Z1LiHNp8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}