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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a61c6de9490653a2c0c89ae9d6680d62251a01eddf49524b6e97b5c59393099' 
  AND token = 'N0rVHbFqrM/R2IsHjeTabSwQeiO2EWd1SvOwZzDN1yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}