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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f241140c46997a166a7a3f5d0f5156cb264b8d726675bd8f93b5e4a691ac1cd' 
  AND token = '+bXBTz9Ej3XfzfXI19iHtudNN+4VMn4PNCm4Niz0eT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}