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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f2f2a42928c56a0f452a01b176dea16bbe38f6b13bf99e11227f77365bc2aed' 
  AND token = 'NO7Zq7DdN/WlqaT4otTEuTAJBdKH3e3D8A/KZHI3mbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}