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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d78e0e9010d956ee42f6bc35a43feffde29f78e18b7ffc838517ef409654bf' 
  AND token = '+FSgN4cinTYEh+il0A/G36BRdb3KoVgCdUKKpXAG+bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}