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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd641857d32701f067de2817c26df4b6127d61988e3bce9e90cb6f20abb36f5d' 
  AND token = 'G2EPtZkqNFjtaFOe41UxQ+KM8TBR32oFlg6BWDcNUv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}