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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3bd0858a745a2e86b34380a424fbb5fcb089412789b8fded9cf11aadaf3c60e' 
  AND token = 'a5r3r66GORY6LXSwfUAron15q6tnLEB3Lv1qY8XZZzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}