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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26cd908032cd7401bf46eea4fc2018c457f0229a2a060045123595241a9f945b' 
  AND token = 'B9XrOhTFvXUQdVB+MMnq4GRdHkEaEzfzeh4SsO2AK6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}