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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21756acd1104a7a2a5127b7cd0a1b4cc9f9c706c01bc61d04c9c98015f8355c5' 
  AND token = 'Pys5uWd0SgKQKTopJpcOuBwYze2MuV8WlNM+SoEsVa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}