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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7720c7597b9be059ef7807186cda2a956fe283f75010806561c3afe3891f3d03' 
  AND token = 'O/9pHWk9AW16SP4gsSNDySCFL3Zia5HBlZqAk9ML7uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}