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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd543f099889c12fddaef5e5c1cbfbb41ca0aac2f5a7c5967a5e0286a4c9644ff' 
  AND token = '0JhUDwVUOHhSA80DKz2xRKu1jff0qH8O85JUe7hc+nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}