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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d53a07209111e1327525a5fa258d553f22b98da57767a0553670e6173fb471' 
  AND token = 'kGTAuOBj/ctMht78plhofYPkGW+WOGdh0jiOTS5dc0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}