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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c848ec61f7b45c03651d66012f35d736beb3cdc410984f5a30813e586420cc4' 
  AND token = 'C7b8z4W1OgJ/6+/+RoaKH5wPbaeVzQhzCMf4JbruTmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}