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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0a559437c806430fea3eb2b80f1e1cc7f146dffa7360fc148ba75d10ae7d930' 
  AND token = 'HPDdMa1fCwVXLTurp52TXe7CTUjI31qgLZZ2t8g5dsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}