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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c2d49d03d2af4c3b8b387841bb876bebd42d0be3c4b7b58415edc9df7df823' 
  AND token = 'gDjpy8Y4w4loIveQPIM0UHZ6IbClMMPgqlbG+wp6ZcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}