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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f951b9ecde8d2aa36653dde76290a5a5e62eeadb4d7b188139ab025f60ee7c' 
  AND token = 'ymm2yM2+jchV1hq4ebwU/aJk0Fw3IIr/17G2nc0deN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}