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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ee3fe23fe87e397ecd421e7674678031c409a6886137d7458c29d5e7c2713c' 
  AND token = 'Ln+hTTFQ6NgNZK7FrUmRs9JZ5SUzFgBuGpPtYewZ1sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}